By Jürgen Engel
This monograph offers a finished and up to date strategy on biomineralization. The topical concentration of the publication lies at the query of the way matrix proteins and cells catalyze and keep an eye on mineralization in organisms. contemporary advances within the figuring out of biomineralization support to raised comprehend biomaterials, particularly their mechanical houses. the objective viewers essentially contains practitioners and study specialists within the box, however the booklet can also be priceless for graduate scholars.
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Extra info for A Critical Survey of Biomineralization: Control, Mechanisms, Functions and Material Properties
The sequences of amelogenin (Fig. 5), ameloblastin, and enamelin (Fig. 7) share no clear homology with other proteins. Nevertheless, the three proteins are believed to be members of the so-called Pro-/Gln-rich SCPP (secretory calciumbinding protein) family . ASPARC/BM40, a calcium-binding protein of the Fig. 7 Protein sequence of murine ameloblastin precursor, isoform 2. So far, no homology with other proteins was detected 26 5 Enamel is the Hardest Biomaterial Known basement membrane, is also believed to be a member of this family.
Recently, much more detailed information has been obtained by a sophisticated technique, namely solid-state NMR [1, 2]. In one study, the R5-peptides of silafﬁn (Fig. 7) were added to silicic acid © The Author(s) 2017 J. 1007/978-3-319-47711-4_8 51 52 8 In Vitro Studies of Mineral–Protein Interactions and the biosilica composite was examined by solid-state 13C two-dimensional magic angle spinning NMR . It was conﬁrmed by scanning electron microscopy that biosilica nanospheres with a diameter of 500–750 nm were formed.
VDM Verlag Dr. Müller Chapter 10 Biomineralization Processes for Future Research This book has centered on three biomineralization systems, namely enamel formation, mollusk shell formation, and the building of diatom glass houses. These systems at present offer many insights into the molecular mechanisms of biomineralization. Research by modern methods of molecular genetics and molecular biology has progressed well in all three ﬁelds. It should not be forgotten that, compared with the enormous number of biomineralization systems (for a survey see [1–3] and references in Chap.